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Voichiţa Bar Ad, M. The clinically negative neck of the patients with HNSCC may be managed with observation only, elective neck dissection or elective radiation therapy.

There are no large prospective randomized trials comparing between these treatment options.

The principal aim of treating electively the clinically negative neck in patients with HNSCC, by ei­ther surgery or radiation therapy is to maximize the rate of control of the disease in the neck. It remains to be proven if the elective neck treatment contributes to improved overall survival for the patients with HNSCC and clinically negative neck.

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  2. Sunteți pe pagina 1din 31 Căutați în document Studii clinice Prostatectomia radicala retropubiana analiza retrospectiva a perioadei C.

Hatieganu University of Medicine and Pharmacy Cluj-Napoca Vulvar cancer is a highly curable tumor if it is diagnosed in an early stage.

Survival is strictly correlated with the pathologic status of inguinal lymphnodes which, together with primary tumor dimension, represents the most important prognostic factors. Primary sur­gery remains the main curative treatment method and consists of modified radical vulvectomy with the bilateral inguinofemoral node dissection, with a minimum number of 10 excised lymphnodes.

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New data are available regarding the sentinel lymph node concept in vulvar carcinoma, and, also surgical techniques in order to diminish acute and late morbidity.

Key words: Vulvar Cancer, Inguinofemoral Lymphadenectomy.

We analyze the prostate IMRT process from the prostate motion management and setup uncertainty perspective.

The use of image guided daily setup or radiofrequency markers for continued tracking and quantitative characterization of uncertainty margin will help to realize the full potential of IMRT for the prostate.

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Ciuleanu1,2 1Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca; 2Ion Chiricuta Cancer Center, Cluj-Napoca Although over the past decades the incidence of unknown adenopathies has decreased these categories of patients represents considerable difficulties, due to many diagnostic and therapeutic problems for the oncologist. On the other hand in order to opti­mise resources, we must be careful to do the minimal number of diagnostic examinations necessarily for the diagnosis from the point of view of prognosis or types f treatment such as: breast cancer, prostate, lymphoma, neuroendocrine tumors, thyroid cancer, germinal tumors.

The authors have tried to suggest a guide for physicians interested in the diagnosis and treatment of this category of patient. Key words: Adenopathies, Therapy.

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Primary endpoints were disease-free survival and disease specific survival. Patients and methods: Between January — December54 patients with laryngeal cancer, who had radical resection followed by postoperative radiotherapy at the Cancer Center Ion Chiricuta Cluj Napoca, were included.

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The extracapsular extension influenced disease free survival. The secondary objective was to correlate LN metastasis with other prognostic factors.


Patients and methods: The study included pa­tients with advanced cervical carcinoma treated in the Oncology Institute, Cluj-Napoca between March and Augustwith RT±CT, followed by surgery radical abdominal hysterectomy tratamentul prostatitei komsomolsk pe amur bilateral pelvic lymphadenectomy -Wertheim operation- WO.

The pathologic evaluation of the surgical specimen specified the number of the dissected LN, the residual tumour cells in the cervix and the endometrium, in parametrial tissues, psa nadir after prostatectomy the vaginal margins and in the pelvic LN.

Conclusions: The LN status psa nadir after prostatectomy an important prognostic factor in cervical cancer, regarding the number of dissected lymph nodes and the presence of metastases. Spiridon Hospital, Department of Radiotherapy, Iaşi; 3IuliuHatieganu University of Medicine and Pharmacy Cluj-Napoca Purpose: To perform an evaluation of toxicity and to report preliminary results of three dimensional conformal radiotherapy 3D-CRT for treatment of localized prostate adenocarcinoma in current practice in Romania.

Only 3 patients had RT as salvage therapy for isolated locally confirmed recurrence after radical prostatectomy. The first 46Gy were administered using a four conformal field arrangement to prostate, seminal vesicle or up to 54Gy to prostate and seminal vesicle in case of T3b while the boost was given by a six field technique to prostate only plus lower half of SV if T3b.

The planned doses were Gy for high and medium risk patients, Gy for low-risk, Gy for local recurrence following radical prostatectomy and 46Gy for those patients re­ceiving brachyterapy boost. In all cases standard fractionation fr.

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Toxicity was scored using the CTC3. Results: With a median follow-up of 18 months months there were 2 biochemical failures at the time of analysis, one due to distant recurrence.

Severe acute toxicities were remarkably low with Grade 3 urinary morbidity in 7. Late severe urinary effects grade 3 were seen in 3. No late severe digestive toxicity was reported.

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Conclusions: 3D-CRT reveals better tolerance, significantly less acute and chronic toxicity compared with conventional techniques and ap­parently yields higher biochemical disease-free intervals, although longer follow-up is needed to determine the impact on long-term outcome and late sequelae.

Vavassori1, F. Cattani2, C. Fodor1, L. Santoro3, V. Matei4B.


Jereczek- Fossa1,5, O. De Cobelli4, R. We present the out­come data of these patients. Methods: Data was analysed from a retrospective database of consecutive patients, median age 70 years range years treated with permanent prostate brachytherapy between October and July Patients were stratified into low Patients received Gy brachytherapy BT as monotherapy Results: Median follow-up was 46 months range months.

Prostate cancer-specific mortality at 7 years was 2.

PSA Levels After Prostate Cancer Treatment

Taking into account the PSA bounce, only Psa nadir after prostatectomy LDR prostate brachytherapy performs an excellent cause specific survival, a low toxicity and a good biochemical control in low risk psa nadir after prostatectomy. One had a partial response; the disease stabilised in the others. There were marked reductions in non-target lesions, and improvements in dis­ease-related symptoms and quality of life. Key words: Non-small-cell Lung Cancer, Erlotinib.

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  • This book reviews the use of PSA as a biomarker and the various aspects of the possible role of PSA in prostate cancer.